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So far, there isnt a clear cause
Recommendation 3.1: Provide clients with, or refer them to, intensive interventions and counselling on the use of pharmacotherapy, if they use tobacco and express an interest in reducing or quitting their tobacco use
www.cdc.gov/tobacco/php/data-statistics/smoking-cessation/
Formaldehyde, which has been linked with leukemia and respiratory cancers
Sixth, although some studies have begun to characterize the impact of smoking on gray matter in young adult/adolescent smokers [85, 86], the concurrent influence of marijuana [111] or alcohol use [112], and sex differences among smokers [17], as more studies accumulate regarding the influence of these and other important factors on gray matter alterations, it will become possible to better characterize the specificity of the meta-analytic effects identified herein