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There's no tobacco product that's completely safe

"The Council's landmark action will help prevent the tobacco industry from addicting another generation of kids." The Centers for Disease Control and Prevention has said any use of tobacco products by children and teenagers is unsafe, but most use begins with flavored products

The Guardian, 2022

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Experience helps mitigate this effect as the body becomes more accustomed to the action of nicotine

Most e-liquids contain a mix of propylene glycol and vegetable glycerin chemicals that might seem safe for ingestion but are largely untested for long-term inhalation