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It briefly stimulates the brain by increasing dopamine and epinephrine, then produces calming or depressive effects as those chemicals drop

He had previously been smoking 20 cigarettes a day for 30 years before starting to use electronic cigarettes to aid his smoking cessation

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"What we are proposing is a high-calibre centre that will involve senior analysts and will use a variety of resources and tools, to provide the factual information that will seriously counter the risk activists and their misleading and misguided propaganda," the letter said

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