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Journal of Investigative Medicine, 70(1), 513

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Once the pharmaceutically branded forms of this medication is removed from the shortage list, compounding pharmacies will no longer be able to create compounded versions

Safety Advice Liver Disease No dosage adjustment for Rybelsus is generally needed in patients with mild to moderate hepatic impairment

A 2024 race and ethnicity analysis pooled STEP 1 and STEP 3 and reported participants as White 75.3 percent, Black 8.8 percent, Asian 10.6 percent, and other 5.3 percent

CONCLUSION MetALD represents a major unmet need in hepatology, and current management relies largely on extrapolation from separate MASLD/MASH and ALD trials that systematically excluded patients with overlapping metabolic dysfunction and clinically meaningful alcohol exposure