how many people smoke tobacco in the us Why a group of U.S. states smokes more than a less-developed country Tobacco Product Use Among Adults

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POLYMORPHISMS ASSOCIATED WITH NICOTINE ADDICTION IDENTIFIED BY THE CANDIDATE FUNCTIONAL GENE STRATEGY In the studies of candidate genes, polymorphisms associated with nicotine addiction have been identified in gene encoding proteins involved in the reward and pleasure mechanisms in the central nervous system

Teneggi et al ., 2002