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Description

The downstream effects of NNMT inhibition by 5-amino-1MQ create a cascade of beneficial metabolic changes at the cellular level

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injection of the IgG1 teprotumumab (Tepezza) is an approved therapeutic with this mode of action [405,406,407], and others are in development (veligrotug, VRDN-002, IBI311, and ZB001 [NCT05480579, NCT05176639]) [408, 409]

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