Dysregulation of this pathway can bias TRP metabolism toward neurotoxic and pro-inflammatory metabolites, thereby amplifying excitotoxicity, oxidative stress, and immune-driven disturbances in glutamatergic and monoaminergic neurotransmission
Editor information Editors and Affiliations Rights and permissions Copyright information 2022 Springer Nature Switzerland AG About this entry Cite this entry Carmo de Carvalho e Martins, M.d., da Silva Santos Oliveira, A.S., da Silva, L.A.A., Primo, M.G.S., de Carvalho Lira, V.B
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Vitamin D: recent advances, associated factors, and its role in combating non-communicable diseases
Although changes in the GABA/Glx ratio have been reported in other diseases (73, 7880), association with decreased NAA and increased Glx/NAA may be specific to ALS