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doi: 10.1007/s00421-019-04293-5, 62

While our data do not support a general reduction in motivation, a clear dissociation between drug-directed and general motivational effects would require additional control conditions such as non-drug saline IVSA

Insider Tip: Tolerance and habituation are different from addiction, which involves an inability to control your use even when you want to and developing a dependence on it for daily functioning, among other things.76 It is possible to become addicted to some nootropics, though its not common

The rationale for this approach was to investigate if GLP-1 signalling could cause metabolic reprograming that would persist after removal of receptor stimulation (Fig