Grading of recommendations Recommendations are graded according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system.21 Whether a recommendation is strong or conditional will depend on considerations such as certainty in estimated effects of an intervention, including magnitude, as well as estimates of how patients value and prioritize outcomes, variability of these estimates, and wise use of resources
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You might have heard your friend say it on a night out, maybe from a stranger looking to bum a smoke, or maybe youve even said it yourself
Its important not to adjust your dose without consulting your physician or healthcare provider
