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The decision to defer GH therapy in this adolescent with advanced disease was based on a riskbenefit assessment, weighing the potential benefits against the known risks of exacerbating pre-existing severe OSA and respiratory failure in the context of morbid obesity

This rapid clearance is one of its key safety features in a research context

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The most common adverse events reported in clinical trials have been mild gut symptoms including nausea, headache, and abdominal discomfort, which were often transient