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A rational policymaker would complement smoking-cessation and- prevention programs with a tobacco harm-reduction strategy, ensuring that nicotine users experience the least possible harm consistent with their own risk preferences

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We focused on individuals with low SES and with SPD because they are, respectively, the largest subpopulation with significantly elevated smoking prevalence and a subpopulation with very high smoking prevalence [9,10,11, 16,17,18, 42]