Sleep protocol: Set a consistent bedtime and wake time, including weekends
Ive had minimal side effects (slight nausea and sleepiness day of and day after an injection)
Considerations when switching Currently, there is no NICE or Medicines and Healthcare products Regulatory Agency guidance that specifies how to switch between tirzepatide and semaglutide
Dosing and Administration Both medications are administered via weekly subcutaneous injections, making them convenient for patients
Secondary analyses included stratification by demographic and clinical variables (sex, age, race, eGFR, HbA1c, hypertension, medication use), and extended follow-up for long-term drug effect assessment
Low concentration (5 mg/mL): larger volumes, easier measurement At 5 mg/mL, doses require more liquid