does chewing tobacco affect fatty liver Smoking and diseases: an updated review of pathogenesis, progression, and therapeutic implications Connection of Nicotine to Diet-Induced

PMID 39709381

The liver naturally contains some fat, but when more than 5% of hepatocytes (liver cells) are affected by fat accumulation, it becomes pathological

Chewing Tobacco and Fatty Liver: Understanding the Link Chewing tobacco and fatty liver disease represent two significant health concerns that may be more connected than many realise

Some observational studies suggest that patients with NAFLD who continue using tobacco products may have higher rates of advanced fibrosis compared to non-users with similar metabolic profiles, though the strength of evidence specific to smokeless tobacco remains uncertain

That, in turn, can lead to chronic inflammation, which has been linked to both the development and spread of certain types of cancer

26th ed