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We also tested the sodA and spxB mutants that have previously shown a lower phenotype than wt [6, 32], although these strains displayed a higher H 2 O 2 resistance than the mentioned mutants, but significantly lower compared with the wt strain (Fig 3B, Fig S2)

Results obtained by western blotting confirmed that GPX4 is strongly upregulated in 3D spheroids compared to the 2D cells, without substantial modulation following treatment

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H.ChingaF.et al (2015)

Prophet, E