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Beyond anecdotes, are some observational studies and animal experiments suggesting they might help with addiction (OKeefe et al

There have also been reports of lipase catalysis where the reaction proceeds with solvent quantities of one of the reagents 3,12,13 , where the lipases are typically present as either a lyophilized powder 12,13,26 , or immobilized on a substrate 2,3,8,10,27,28 , but there are no examples of molecularly dispersed enzymes catalysing reactions in the complete absence of a solvent

Weights were measured during clinic visits and were categorized by time from initiation of GLP-1 RA at 6 months or 12 months

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Is this combination beneficial or risky

Bailey et al., 2023)