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Although we did not find an effect using multiple genome-wide significant genetic variants, we noted that one SNP (rs3804640) stood out in particular, showing a large positive effect of bipolar disorder on smoking initiation and lifetime smoking in the single SNP analysis (supplementary Figs 5, 11)

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Ashes to ashes, indeed.

Exiting Drug War Chief Warns of Cartels. New York Times, October 31

Suppose the rent for a typical apartment had been R 0 and the quantity Q 0 when the demand curve was D 1 and the supply curve was either S 1 (a supply curve in which quantity supplied is less responsive to price changes) or S 2 (a supply curve in which quantity supplied is more responsive to price changes)