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One of the more interesting aspects is that while the CS exposure depletes the ELF, plasma, and liver GSH levels, the lung tissue GSH levels remain unchanged

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Safia Pirani MD

Two possibilities are that DHA concentrations are extremely low in compartments such as the chloroplast and cytosol or that rate constants for the chemical reaction are much slower in the crowded cellular environment than those measured in dilute solutions in vitro, making enzymes necessary to favour the reaction between DHA and GSH