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The lifelong developmental disability affects social interaction, communication, interests and behavior that begins early in childhood and lasts throughout a persons life

Blood markers may change before nerve symptoms improve, and long-standing neurologic symptoms may take longer to assess

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J Anesth 22:397403 Newman-Tancredi A, Nicolas J-P, Audinot V et al (1998) Actions of alpha2 adrenoceptor ligands at alpha2A and 5-HT1A receptors: the antagonist, atipamezole, and the agonist, dexmedetomidine, are highly selective for alpha2A adrenoceptors