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The system consists of a combination of sensitive feeding sensors for automated measurements, gas calorimetry to calculate the energy expenditure of each mouse, and a photobeam-based activity monitoring system for detection and recording of ambulatory movements including rearing and climbing, in each cage

Ipamorelin is a synthetic pentapeptide belonging to the group of ghrelin mimetics, acting as a selective agonist of the GHS-R1a receptor (Growth Hormone Secretagogue Receptor)

The severity of colon mucosal damage was evaluated using the colonic mucosal damage index (CMDI) following the criteria outlined by Jiang et al