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For cigarettes only users, 41.8% ( n = 408) report that they will not use e-cigarettes in the future, 30.9% ( n = 301) use both cigarettes and e-cigarettes in the future, and 27.3% ( n = 266) would give up cigarettes and use e-cigarettes

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These habits may affect the activity of the mitochondrial respiratory chain as well as the replication and transcriptional regulation of mitochondrial genes, leading to altered mitochondrial function and, in turn, to psychiatric disorders 59