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But the article contrasts these risks with the unambiguous harmful agents in cigarette smoke70 carcinogens, as well as carbon monoxide (a poison), particulates, toxic heavy metals such as cadmium and arsenic, and oxidizing chemicals
Li Z, Guo H, He H, Wang S, Pei S, Xie L
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2020 titled Nicotine Addiction: Neurobiology and Mechanism. These changes lead to cravings and a heightened sensitivity to triggers associated with tobacco use, such as stress, social situations, or environmental cues
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Nicotine itself, separate from smoke inhalation, exerts powerful effects on healing processes
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