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These include a body mass index (BMI) of 35 kg/m or above (or 32.5 kg/m or above for people from South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean backgrounds) with at least one weight-related comorbidity, and previous unsuccessful attempts at weight loss through diet and exercise

Chen, X., Zaro, J

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[16] However, it should be noted that the article was written before equine metabolic syndrome was well recognized and the role of insulin was known