One primary endogenous source of ROS is the enzyme NADPH oxidase (NOX), which catalyzes the transfer of electrons from cytoplasmic NADPH to molecular oxygen, resulting in the formation of superoxide anions that react with NO to form peroxynitrite, a highly unstable species that can generate further ROS [21,22]
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Well, when something is burning, it creates hot air around it
Supplementary material The Supplementary Material for this article can be found online at: References 1 AdamowiczS