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Although smoking is a risk factor for MI and CVA, based on temporal relationship between medication use and events, a contributory role of varenicline cannot be ruled out [see Warnings and Precautions (5.5)]

This general position has also long been accompanied by an industry-wide insistence that advertising did not target youth and that exposure to advertising by youth was the incidental consequence of a spillover effect of targeting young adult smokers

FLAVORLESS FLAVORLESS Does not contain flavoring and is odorless

We noted a moderate degree of heterogeneity across the studies (I 2 =71%, p=0.07) (Figure 3)

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