Pregnancy and breastfeeding: GLP-1 receptor agonists are not recommended during pregnancy or breastfeeding
doi:10.1152/japplphysiol.91004.2008, PMID: 18845776 Soejima Y, Ostrowski RP, Manaenko A, Fujii M, Tang J, Zhang JH (2012) Hyperbaric oxygen preconditioning attenuates hyperglycemia enhanced hemorrhagic transformation after transient MCAO in rats
They've been actually excluded from the trials
However, analysis by Nice found these drugs are under-prescribed
Importantly, Mounjaro delays gastric emptying, which may affect the absorption of oral medicines, including oral contraceptives
Background Several medications reduce antipsychotic weight gain, including metformin, topiramate, and the partial opioid antagonist samidorphan (available as an olanzapine combination pill, Lybalvi)