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Significantly higher abundance of Streptococcus was observed in healthy individuals compared to OSCC samples, non-consumers of smokeless tobacco compared to smokeless tobacco consumers among healthy samples, and contralateral healthy site compared to tumor site in OSCC samples

Funding This work was supported by the Spanish Ministry of Science and Innovation [Grant Number SAF2017-89714-R]

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An update of this study was initiated in November 2021 with the aim of bringing the literature search up to date and incorporating feedback received during the presentation of this work to the scientific community