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We consider that reducing the undesirable compounds in smoke is certainly of great importance, but selectively reducing the most undesirable compound is likely to be the most effective way of lowering the risk of smoking

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Where possible, treatment effect for each Arm pair comparison will be expressed using the Hodges-Lehmann estimator with the 95% confidence intervals and significance levels

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Five hundred microliter of the methylene chloride layer containing the nicotine was then vortexed with 500 l of 50 mM HCl solution and the nicotine of the HCl solution was estimated by HPLC analysis at 254 nm