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Spatiotemporal Delivery of Dual Nanobodies by Engineered Probiotics to Reverse Tumor Immunosuppression via Targeting Tumor-Derived Exosomes

In expressions [ 15 ], l is defined as any arbitrary one-dimensional length of the brain (for example, rostrocaudal length of the brain), used only for defining the one-dimensional proportion (l 2 /l 1 ) between two observed brains and as an inter-factor (and because of that not measured [6] ) for deriving final expression [6]

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These methods can achieve bioavailability approaching injection levels while avoiding needle phobia concerns