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The three non-coded amino acid substitutions serve critical functions: Aib2 provides stability against dipeptidyl peptidase-4 degradation, Aib20 optimizes GIP receptor activity and pharmacokinetic properties, and alpha-methyl-L-leucine at position 13 enhances receptor binding selectivity[2]

Chemical compounds and reactions capable of generating potential toxic oxygen species can be referred to as prooxidants

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BrodzkaSBaszyskiJRektorKHoderna-BonaKStanekEKurhalukNet al

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Furthermore, these epithelial components express various surface receptors, including TLRs to sense endogenous danger signals, or pathogen-associated molecular patterns (PAMPs) to detect microbes