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They are up-regulated during the activation of microglia following brain injury, (Ashton and Glass, The Cannabinoid CB2 Receptor as a Target for Inflammation-Dependent Neurodegeneration)

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Further reading [edit] The Tobacco Monopoly in the Philippines: Bureaucratic Enterprise and Social Change, 1766-1880

And theres also the forthcoming film version of Joyce Carol Oatess Blonde, a fictional biography of Marilyn Monroes interior life, directed by Andrew Dominik