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doi: 10.2147/copd.s2654 62

Based on biophysical considerations derived from patch-clamp studies on Slow Vacuolar calcium channels, likely to be identical to TPC1 (Pottosin and Schoenknecht, 2007), this tonoplast channel has been proposed to act as major driver for release of Ca 2+ from the vacuole into the cytoplasm, rather than as uptake channel