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These medications include semaglutide (Ozempic, Wegovy) and dulaglutide (Trulicity) for both diabetes and weight management, and liraglutide (Victoza for diabetes, Saxenda for weight management)

Meta-regression was carried out to explore the possible sources of heterogeneity, such as the baseline degree of obesity involved above ( Statistical analyses were performed using Stata version 160 (Stata Corp, College Station, TX, USA) and R software (version 413)

Among these Americans, the top reason is a preference to manage weight through traditional methods, as well as concerns over side effects

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The proposed anti-inflammatory mechanisms of GLP-1 receptor activation, primarily observed in preclinical models, involve several pathways