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These chemicals enter tobacco products through multiple routes: Naturally occurring in the tobacco plant: Tobacco plants produce biological chemicals such as nicotine (the main addictive substance), polyphenols (which affect flavor), and toxic metals absorbed from the soil

Heating tobacco at lower temperatures than combustible cigarettes allows nicotine to be delivered in ways that retain much of the ritual and experience of smoking, writes the report's author Dr

The effects of tobacco control policies on global smoking prevalence