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Purpose: Both recreational and medicinal purposes Date Submitted: September 16, 2021 United States of America | 35 to 44 Year Old Female (Using for 11+ years) brain fog, gastrointestinal issues Habit: a lot Brain Fog Experienced: Most of the day Activities Disrupted: Schoolwork Timing of Symptoms: a few days after stopping Purpose: Both recreational and medicinal purposes Date Submitted: September 16, 2021 United States of America | 18 to 24 Year Old Male (Using for 1-2 years) Feel like I dont exist Brain Fog Experienced: All day Activities Disrupted: Work productivity Timing of Symptoms: After an anxiety attack Purpose: Recreational purposes only Date Submitted: September 15, 2021 United States of America | 18 to 24 Year Old Female (Using for 0-6 months) Loss of memory, sometimes I feel not in touch with self, extreme anxiety attacks, unable to sleep, or eat Brain Fog Experienced: Most of the day Activities Disrupted: Work motivation Timing of Symptoms: Nighttime Purpose: Recreational purposes only Date Submitted: September 15, 2021 United States of America | 25 to 34 Year Old Male (Using for 3-5 years) Mood swings, loss of appetite, difficulty remembering recent events Habit: 1 joint a day Brain Fog Experienced: A few hours each day Activities Disrupted: Work productivity Timing of Symptoms: After 2 days of quitting

doi: 10.2174/1570159X19666210712151556, 75

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Jaakkola, J

For the naturalistic smoking task data, smoking events were defined based on the recorded output of the opto-electronic device