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Researchers have been particularly interested in how TB-500 could serve as a simplified model to study cellular motility, tissue organization, and responses to external stimuli

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(2021) 118:e2109721118

471 According to the PAKT trial, the addition of the AKT inhibitor capivasertib to the first-line paclitaxel therapy for TNBC resulted in significantly longer PFS and OS, especially in tumors with PIK3CA/AKT1/PTEN alterations