doi:10.1186/s12937-024-00995-5 Tzang CC, Chi LY, Lin LH, et al
He and his colleagues showed how cancer cells generated and used antioxidants to stay alive
Cigarette smoke can reduce the expression of Frizzled receptor 4 (FZD4) in alveolar epithelial cells and enhance the phosphorylation of -catenin, inhibiting epithelial proliferation and alveolar repair mediated by the classic Wnt signalling pathway
Oxidative stress occurs when there is an imbalance between the production of free radicals and the bodys ability to detoxify them
C-met binding was examined at two HGF-doses (250 ng/ml and 500 ng/ml in PBS) by sandwich ELISA-like assay on recombinant c-met-Fc chimera as in Figure 1e, and significant changes in optical absorbance subtracted by a baseline level (negative control without HGF, bar 1 ) were depicted in Figure 2a (left column)
N Engl J Med 387(3):205216