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to eliminate exposure to all tobacco products, including cigarettes and e-cigarettes. Owens also cautioned against vaping, saying that nicotine is a health concern regardless of the tobacco-free devices

The reviews meta-analysis of 600 records found that e-cigarettes can help smokers unable to stop smoking

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Consistent with nicotines anti-inflammatory effects, chronic nicotine administration via an osmotic minipump did not increase either TNF- or IL-1 in the nucleus accumbens in male mice (160), thereby supporting the notion that the constituents in the JUUL pods, or the interaction of nicotine with the constituents, led to the changes in inflammatory markers

N Engl J Med 2019;380:2460.ArticlePubMed 96