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This combination of factors, in turn, causes a hypoxic microenvironment and mitochondrial dysfunction (McGarry et al., 2018), promoting inflammation and oxidative damage by increasing the production of ROS (McGarry et al., 2018)

The pathogenesis of the cataract in an early age individuals with G6PD deficiency might be shows that the enzyme plays an important role in the lens metabolism

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Over eight weeks, patients receiving empagliflozin exhibited greater reductions in depression severity compared to the placebo group, supporting the hypothesis that metabolic and inflammatory modulation may enhance antidepressant response [280]

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