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And it is treatable

Supply Side and Demand Side Indicators 6

An upper GI endoscopy assesses the mouth, esophagus (the tube that connects the mouth and stomach), stomach, and duodenum

Look at what they said: "No clearcut case against cigarette smoking has ever been made despite millions spent on research ...The longer these tests go on, the better our case becomes." (Phillip Morris, 1968) It took 50 years to induce lung cancer in laboratory animals forced to breathe tobacco smoke (remember those pictures of rows of smoking beagles with cigarettes fixed in their masks?), thus delaying the health warning to humans and resulting in millions more unnecessary deaths

Sawane H, Rajpurohit L, Mathur A, Sonawane S, Kharat P (2023) Smokeless tobacco use and its association with type 2 diabetes: a case control study

If the creatinine clearance is between 3050 mg/dl, the dose may be reduced