It is plausible that the decreased testosterone level is associated with testicular dysfunction rather than a pituitary disorder
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Altogether, the effects of smoking on BP and arterial stiffness remain controversial, while increased AIx has been documented in many studies but the underlying mechanisms are not well understood
The toxic components of cigarettes, such as cadmium, have been suggested to interfere with the function of Leydig cells in the testes, which are responsible for testosterone production
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