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In animal models finerenone reduced the expression of genes encoding monocyte chemoattractant protein-1, matrix metalloproteinase-2 and plasminogen activator inhibitor-1 (related to tissue remodelling and fibrosis) in the kidney, and additionally demonstrated beneficial immunomodulatory effects [73]

doi: 10.3389/fmicb.2023.1204122 43 GaoL.LiuY.YeL.LiangS.LinJ.ZengJ.et al

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