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Graaf C, Donnelly D, Wootten D, Lau J, Sexton PM, Miller LJ, et al

Unlike oral supplements, an injection delivers vitamin B12 directly into the body without relying on digestive absorption which can be reduced by age, certain medications such as proton pump inhibitors or metformin, or gastrointestinal conditions

Life Sciences, 2019

Best administered on an empty stomach (fasting) for optimal GH release

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Impairment of ETC causes excessive ROS, disruption of the electrochemical potential of the proton gradient, insufficient ATP production, and even cell death