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iScience 27 , 111262 (2024)

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In light of the effectiveness of the variable MSR/MLR policy described above, we are proposing to sunset the requirement at 425.110(b)(2) that CMS will terminate an ACO's participation agreement and determine that an ACO is not eligible to share in savings for that performance year if an ACO's assigned population is not at least 5,000 by the end of the performance year specified by CMS in its request for a CAP

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A total of 393 hypermethylated and 184 hypomethylated DMRs (Supplementary Data 3) were identified, with nicotine cessation effectively reversing the aberrant DNA methylation in these regions (Fig