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Corticosteroids and 5-aminosalicylic acid are conventional IBD medications, but they sometimes have limited effectiveness and may cause side effects such as diabetes and kidney problems (153)

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When symptoms do appear, they are often vague and easily overlooked: Because obvious symptoms are often absent, the condition is frequently discovered accidentally during blood tests (showing elevated liver enzymes) or imaging scans (such as ultrasounds or CT scans) performed for other reasons

Authors contributions LT, WW, WZ and KC performed the experiments

Other immune cells, such as neutrophils, B cells, and T cells, are recruited by chemokines

The mechanisms operate in entirely separate biological pathways