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In a combined multiple ascending dose (MAD) and Phase 2a study in people with type 2 diabetes over 41 days, the safety of cotadutide was confirmed (83)
The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, each step being facilitated by a specific enzyme
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In the AMPLITUDE-O trial, patients with an eGFR as high as 71.5 ml/min/1.73m2 were included in the CKD group [7]
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Am J Physiol Renal Physiol (2013) 304:F13744
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