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Along with increases in abdominal fat and total body fat mass, menopause also changes how the body metabolizes glucose

Ludvik, B., et al., Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial

Semaglutide exposure was inversely related to body weight

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Oral semaglutide requires a higher dose than injectable medication since the bioavailability is lower