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Likewise, hypovitaminosis D has been widely reported in obese patients prior to surgery

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Activation of melatonin signaling promotes beta-cell survival and function

NO is an active molecule produced by the nitric oxide synthase (NOS) protein family, which directly binds and inactivates iron-containing enzymes [48] or reacts with superoxide anion radical O2 to form a highly active peroxy sulfoxide Nitrates (ooo-), which can attack membrane lipids and proteins of the pathogens, especially protein thiols [49]

Free Radic Biol Med 191:150163 Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ et al (2017) Selenoprotein S reduces endoplasmic reticulum stress-induced phosphorylation of tau: potential role in selenate mitigation of tau pathology

The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature