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Brunner went on to describe compoundings growing prevalence and controversy in light of the emergence of GLP-1 drugs, originally indicated for weight loss and diabetes and sold under brands such as Ozempic, Wegovy and Mounjaro

If side effects persist and remain intolerable despite extended up-titration, a lower maintenance dose may be considered to support adherence and reduce the risk of treatment discontinuation [66]

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Following ingestion of a meal, the GLP-1 levels rapidly increase

A large observational study using US Medicare data expands on prior evidence regarding the association between the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and an increased risk of developing nonarteritic anterior ischemic optic neuropathy (NAION) in older patients with type 2 diabetes

Statin-induced immunomodulatory effects on human T cells in vivo