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Although laboratory studies generally find that fearful messages are effective in persuasion, they have some problems that may make them less useful in real-world advertising campaigns (Hastings, Stead, & webb, 2004)

Journal of Investigative Dermatology, 142 (6), 16071616

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Proteases such as trypsin have specificity for one residue before and after the cleaved bond due to a shallow binding cleft with only one or two pockets that bind the substrate side chains

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