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it has been found for the United States [14], in European countries [12, 15, 30,31,32,33,34,35], and worldwide [36]

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The UK Biobank is a major national health resource including approximately 500,000 participants aged 4069 years 20

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While addiction is the primary health concern with nicotine use in adults, we know that nicotine exposure is harmful for pregnant women and youth